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MIF demonstrates chemokine-like purpose and was discovered as a ligand of both equally CXCR2 and CXCR4. Binding of MIF to these receptors enhances monocyte recruitment and leukocyte chemotaxis (Figure one). In human chondrosarcoma cells, this recruitment is mediated by Gαi proteins and PI3K in T mobile adhesion as a result of upregulation in the t

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